WebA rapid LC-MS/MS method for the analysis of the immunosuppressant cyclosporin A \(CsA\) in whole blood is presented. The method has good precision \(intra-assay CV 5%, inter-assay CV 10%\) and the accuracy is demonstrated by the analysis of UK NEQAS \(n=2\ 7\) and patient \(n=180\) samples. WebLC-MS offers versatility and resolution. Liquid chromatography (LC) is a technique widely used to separate compounds from a sample prior to analysis and is frequently coupled to mass spectrometry. With LC, separation of the sample components is based on the interactions of the compounds with the mobile and stationary phases, and the degree of ...
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