WebBasic Information:Title: Rational Chemical Design of Molecular Glue Degraders (分子胶设计的合理化学)Authors: Ethan S. Toriki, James W. Papatzimas, Kaila Nishikawa, Dustin Dovala, Andreas O. Frank, M… WebThe present invention relates generally to a class of substituted 3-pyridazinyl-2-phenols and 6-(1,2,4-triazinyl)-2-phenols which bind to the Switch/Sucrose Non-Fermentable (SWI/SNF) complex and to von Hippel-Lindau (VHL) E3 ligase complex, in particular, to substituted 3-pyridazinyl-2-phenols and 6-(1,2,4-triazinyl)-2-phenol compounds which bind to SWI/SNF …
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