Elafin and cancer

Author: ntlc

August undefined, 2024

WebDec 1, 2006 · Abstract. B140 Ovarian cancer (OvCa) is a leading cause of cancer-related death of women in the United States and Europe. Three-quarters of patients have locally … Web21 Blood and Marrow Transplantation Program, University of Michigan, Ann Arbor, Michigan. 22 Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: [email protected]. PMID: 34474163 PMCID: PMC8671218 (available on 2024-12-01) DOI: 10.1016/j.jtct.2024.08.021 Multicenter Study

Elafin drives poor outcome in high-grade serous ovarian …

WebJan 15, 2013 · Elafin is expressed in well-differentiated squamous cell carcinoma of the skin and esophagus but is lost in poorly differentiated tumors [ 10 – 13 ]. Elafin was … WebJan 27, 2014 · Elafin increases cellular proliferation in ovarian cancer To further characterize the biological relationship between Elafin expression and poor survival, we analyzed a … open day at the hate fest

Cancers Free Full-Text High Serum Elafin Prediction of Poor ...

WebSep 8, 2014 · The loss of elafin expression during breast cancer progression may promote tumor growth as a consequence of increased NE activity. To address the role of NE in … WebDownload scientific diagram Elafin increases ovarian cancer cell proliferation. (a) Kaplan–Meier analysis for OS in OC patients according to the expression of PI3 probe 41469_at (n=1058). (b ... WebNational Center for Biotechnology Information iowa realty jefferson iowa

Elafin inhibits obesity, hyperglycemia, and liver steatosis in high …

Elafin selectively regulates the sensitivity of ovarian …

WebElafin, IL-6, and TNF-α were significantly higher in patients who died compared with patients who were still alive at 6 months. IL-6 and IL-10 were significantly higher in patients with a drug-related complex rash. Limitations: Retrospective design, limited sample size, and high-risk patient population. WebElafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling Stanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more. iowa realty iowa fallsWebPhase II trials are underway to investigate the therapeutic effects of elafin on post-operative inflammation and the clinical consequences of major surgery. Of particular interest is the … iowa realty insurance

"WebFeb 1, 2006 · For example, the proangiogenic role of WFDC1 6 strongly suggests that this protein, like antileukoproteinase 1 and elafin, 3 also has a role in tissue remodelling and repair—processes that are commonly associated with the inflammatory response, cancer progression, and invasion by tumoral cells. 69 Tumour growth and wound healing are ... " - Elafin and cancer

Elafin and cancer

Cancers Free Full-Text High Serum Elafin Prediction of Poor ...

WebMar 26, 2024 · Elafin is a serine protease inhibitor critical for host defence. We previously reported that Elafin was associated with the recurrence of early-stage hepatocellular carcinoma (HCC) after surgery. However, the exact role of Elafin in HCC remains obscure. … WebJun 4, 2012 · Imbalance between NE and its inhibitors is implicated in the pathogenesis of many chronic inflammatory diseases. We hypothesize that elafin is deregulated during breast cancer progression,...

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WebJul 4, 1996 · The polypeptide chain of elafin has a planar spiral shape with an exposed external part and an internal core part which resembles both the crystal structure of human seminal plasma inhibitor (HUSI-1) [Grütter, M ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure WebSep 17, 2015 · A few studies have reported high elafin expressions in tumors to be correlated with poor prognosis of breast cancer [12,29], ovarian cancer [23] and …

WebJun 9, 2024 · The relationship between Elafin expression and clinicopathological features was analyzed by immunostaining scores and mRNA data of colorectal cancer patients. … WebJan 15, 2013 · Altered expressions of SLPI and elafin have been identified in several carcinomas, and it appears that these aberrations may play a role in tumor formation, stimulation of metastatic potential,...

WebElafin, HE4, and SLPI Constitute a Trio of Overexpressed WAP Genes in Ovarian Cancer Apanel of six ovarian cancer cell lines was screened for expression of WAPgenesbyRT-PCR.WefoundthreeWAPgenes,Elafin,HE4,and secretory leukocyte protease inhibitor (SLPI), variably expressed in the cancer lines. WebMay 1, 2008 · Abstract. 5395 Ovarian cancer (OvCa) affects over 25,000 women annually in the US, with a mortality rate greater than 70%. The poor survival is due in part to three quarter of all patients are diagnosed with advance stage disease. When ovarian cancer is diagnosed in its early stage the 5-year survival rate exceeds 90%. Early detection would …

WebApr 15, 2024 · These multipotent cells can be isolated from diverse tissue sources like bone marrow (BM), adipose tissues (AT), umbilical cord (UC) etc. Current studies suggest that MSCs exert strong antimicrobial activity in direct or indirect way by secreting AMPs and other antimicrobial proteins (Alcayaga-Miranda et al. 2024 ).

WebOct 1, 2011 · Elafin-based therapy is currently being tested in clinical trials in the context of improving clinical outcomes in patients undergoing coronary artery bypass surgery, esophagectomy for esophageal... iowa realty jefferson iowa 50129WebDec 31, 2014 · Elafin is an endogenous serine protease inhibitor. The majority of breast cancer cell lines lack elafin expression compared to human mammary epithelial cells. In … iowa realty jeffersonWebJan 2, 2024 · Thus, the detection of elafin is beneficial to diagnosis and treatment selection. 1. Introduction Ovarian cancer (OC) is known as one of the most lethal gynecologic malignancies, ranking as the fourth … iowa realty license classWebApr 8, 2014 · Celiac disease causes chronic abdominal pain (diarrhea, cramps…) and predisposes to certain cancers (small intestine, lymphoma). Its prevalence is estimated between 1/500 and 1/300; no curative... iowa realty knoxvilleWebSep 14, 2010 · Elafin, an endogenous inhibitor of neutrophil elastase, is expressed in human mammary epithelial cells but is transcriptionally downregulated in breast cancer cells. We … open day ccbWebNov 5, 2024 · Background: A major cause of mortality in patients receiving hematopoietic stem cell transplantation (HCT) is acute graft-versus-host disease (GVHD), a multiorgan disorder that includes the skin, liver and gastrointestinal tract.We have previously identified elafin, a protease inhibitor overexpressed in inflamed epidermis, as a diagnostic … iowa realty jordan creekWebMay 1, 2007 · Abstract. 421 Cyclin E is a positive regulator of the G1 to S phase transition of the cell cycle. Previously, we have reported that cyclin E is overexpressed and present in low molecular weight (LMW) isoforms in breast tumor tissues compared to normal tissues. The frequent appearance of the LMW forms of cyclin E is a very strong predictor of poor … iowa realty jefferson iowa listings